Recent News & Research

*July 2023* A University of Kentucky Markey Cancer Center research team identified an existing cancer drug that shows promise as a treatment for the most common type of non-small cell lung cancer. The study published in the American Journal of Cancer Research shows that the Food and Drug Administration-approved medication crizotinib (also…

*June 2023* EGFR The biggest lung cancer news to be presented at this year's meeting was the final 5-year survival results of the ADAURA trial. This trial, the first of its kind, looked at the use of adjuvant (after surgery) osimertinib (a third-generation targeted therapy for EGFR-positive lung cancer) in patients who had…

*June 2023* Rezivertinib (BPI-7711) showed promising clinical central nervous system (CNS) efficacy among patients with advanced non–small cell lung cancer (NSCLC) with EGFR T790M mutation and CNS metastases.​​ The study included individual data from 2 different single-arm, phase 1 (NCT03386955) and phase 2b studies (NCT03812809) to assess the CNS response of rezivertinib…

*July 2023* Benjamin Besse, MD, PhD, professor of medical oncology at Université Paris-Saclay and Head of Clinical Research at Gustave Roussy, discusses the biomarker analysis of cohort D of the phase 1/1b CHRYSALIS-2 (NCT04077463) study. In the trial, the efficacy of amivantamab (Rybrevant) and lazertinib (Leclaza) is being evaluated for…

*July 2023* Targeted therapies and the complex landscape after progression on osimertinib/Tagrisso. You can now watch it on demand here. It's extremely informative! View the presentation slides here.

*July 2023* With osimertinib (Tagrisso) available as a treatment option in both the metastatic and adjuvant settings for patients with EGFR-mutated non–small cell lung cpatients with EGFR-mutated non–small cell lung cancer ancer (NSCLC) and ongoing trials evaluating combination therapies for this patient population, molecular testing to identify these aberrations in patients with…

*July 2023* The Lung-MAP Accrual Enhancement Committee (AEC) hosted this webinar which featured leading experts from the current Lung-MAP clinical trial to discuss recent trial updates, challenges to the traditional clinical trial landscape that Lung-MAP is working to overcome, and opportunities for patient engagement in the process. Importantly, the webinar featured a panel…

*June 2023* In Hollywood, the word "mutant" generally has a negative connotation, with movie plot lines that involve rogue mutants, mercenary mutants, or hunted mutants. But in the lung cancer space, harboring an EGFR mutation may confer an advantage. In a study that sought to pinpoint survival outcomes for patients with synchronous oligometastatic…