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OncLive
ResearchTreatments

Dr. Spira on the Further Investigations of Lazertinib/Amivantamab in EGFR-Mutant NSCLC

*August 2022* Alexander I. Spira, MD, PhD, FACP, research institute director, Thoracic and Phase 1 Trial Program, Virginia Cancer Specialists Research Institute, Virginia Cancer Specialists, clinical assistant professor, Johns Hopkins University, discusses additional studies investigating the use of lazertinib (Leclaza) and amivantamab-vmjw (Rybrevant) in EGFR-mutated non–small cell lung cancer (NSCLC).…
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September 25, 2022
IASLC
ResearchTreatments

Dynamic Mutation Profiles of SCLC Transformation in NSCLC Patients Harboring Concurrent EGFR/TP53/RB1 Mutations

*August 2022* From WCLC Abstract presented by Dr. Jie Huang Introduction: Small cell lung cancer (SCLC) transformation remains one of the unsettled resistant mechanisms for lung adenocarcinoma (LUAD), of which co-occurring TP53 and RB1 mutations defined a subgroup of patients with increased risk of SCLC transformation. Our study aimed to…
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September 25, 2022
ResearchTreatments

EGFR Tyrosine Kinase Inhibitor Sequencing Revisited: From the Revival of Old Tools to the Integration of New Agents

*September  2022* In this issue of the Journal of Thoracic Oncology, Piccirillo et al. report the results of the BEVERLY trial, a randomized phase 3 study that reveals the progression-free survival (PFS) benefit of bevacizumab to erlotinib as first-line treatment for Italian patients with metastatic NSCLC with common EGFR mutations. In this large study, after…
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September 25, 2022
FDA Food and Drug Admin Logo
ResearchTreatments

FDA grants accelerated approval to fam-trastuzumab deruxtecan-nxki for HER2-mutant non-small cell lung cancer

*August 2022* On August 11, 2022, the Food and Drug Administration granted accelerated approval to fam-trastuzumab deruxtecan-nxki (Enhertu, Daiichi Sankyo, Inc.) for adult patients with unresectable or metastatic non-small cell lung cancer (NSCLC) whose tumors have activating human epidermal growth factor receptor 2 HER2 (ERBB2) mutations, as detected by an…
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September 25, 2022
lungevity
ResearchTreatments

How to Read Biomarker Test Results

Biomarker testing is used among diagnosed patients with  non-small cell lung cancer (NSCLC) to determine the presence of specific mutations or proteins associated with cancer. It ensures that patients get matched to the right treatment at the right time, based on their biomarker test results. The results can also provide…
laurabbook@gmail.com
September 24, 2022
lungcancer.net
ResearchTreatments

Not all EGFR Mutations Are the Same

By EGFR Resisters Cofounder Ivy Elkins for Lungcancer.net Many of you understand the importance of having biomarker testing when you are diagnosed with lung cancer. This biomarker testing may indicate that you have an EGFR-positive mutation. But what does that mean? What does EGFR mean? First of all, EGFR stands…
laurabbook@gmail.com
September 24, 2022