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First-Line Osimertinib/Bevacizumab for Metastatic EGFR-Mutant Lung Cancer ResearchTreatments

First-Line Osimertinib/Bevacizumab for Metastatic EGFR-Mutant Lung Cancer

*July 2020* In the trial, 49 patients enrolled between August 2016 and May 2018 at Memorial Sloan Kettering Cancer Center received osimertinib at 80 mg daily and bevacizumab at 15 mg/kg once every 3 weeks, the maximum-tolerated dose identified in the phase I portion of the trial. The primary outcome…
laurabbook@gmail.com
September 18, 2020
targeted oncology
Almonertinib Induces Response in EGFR T790M-Positive NSCLC With CNS Metastases ResearchTreatments

Almonertinib Induces Response in EGFR T790M-Positive NSCLC With CNS Metastases

*May 2020* The study results indicated clinical efficacy against central nervous system metastases in a cohort of patients. Almonertinib also displayed an overall favorable safety profile. Clinical benefit was observed with almonertinib (HS-10296) as treatment of patients with EGFR T790M-mutant non–small cell lung cancer (NSCLC) who progressed on previous EGFR tyrosine kinase inhibitors…