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Locking Down a Link Between Pollution and EGFR-Mutated Lung NSCLC

*September 2022*

Fine particulate matter from the combustion of fossil fuels seemed to trigger non-small cell lung cancer (NSCLC) in never smokers through a process of “tumor promotion,” according to a study on the etiology of EGFR-mutated disease.

The link was first suggested decades ago and long overlooked, but now appears to be the most likely mechanism of action, said Charles Swanton, PhD, of the Francis Crick Institute and UCL Hospitals in London. Read more.